Oncology and AIDS blog

Bradmer Reports Progression Free Survival Data From Previous Phase II Glioblastoma Multiforme Trials

July 27th, 2008 by allsoch

Glioblastoma. Source neuropathologyweb.orgBradmer Pharmaceuticals Inc. (TSX: BMR), a biopharmaceutical company dedicated to the development and commercialization of cancer therapies, released progression free survival (PFS) data from two previously conducted Phase II trials of Neuradiab(TM) in glioblastoma multiforme (GBM) patients. As an exploratory endpoint of the single arm Phase II trials, the data showed a mean overall PFS of 17.2 months in 19 GBM patients treated with Neuradiab. Bradmer is currently conducting a Phase III clinical trial, termed the GLASS-ART Trial, evaluating Neuradiab as an adjunct therapy to the current standard of care for GBM patients.

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Study Of 31 Countries Finds Wide Variations In Cancer Survival Rates

July 27th, 2008 by allsoch

Study. Source lboro.ac.uk A large study published in The Lancet Oncology has found that there are wide variations in cancer survival rates between and within many countries around the world. Professor Michel Coleman (Cancer Research UK Cancer Survival Group and London School of Hygiene and Tropical Medicine) and over 100 colleagues working on the CONCORD study analyzed 31 countries that provided data on cancer survival. Not only were there variations in survival rates for different cancers between countries, but there was also a disparity in survival between black and white people in the USA.

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Researchers Target Specific Genes, Reduce Cancer Cells

July 27th, 2008 by allsoch

Specific Genes. Source fz-juelich.de A report published on July 18 in the open-access journal PLoS Genetics describes a new approach to fighting cancer. Researchers have located a new type of ultrasensitive genes that seem to control the way cancer expresses itself (cancer-associated phenotypes). It is possible that the growth and survival or tumors and other disease-causing agents may be thwarted if drugs are developed that can target these genes.

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New Research From Rhode Island Hospital May Help Predict Outcomes For Stomach Cancer Patients

July 27th, 2008 by allsoch

Cancer. Source brown.eduResearchers at Rhode Island Hospital have identified two potential molecular markers that may predict outcomes for patients with stomach cancer, one of the most common and fatal cancers worldwide.
According to the study, published in Clinical Cancer Research, patients who had poor outcomes following surgery for stomach cancer also had extremely low amounts of two proteins, known as gastrokine 1 and 2 (GKN1 and GKN2), which are produced by normal stomach cells.

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Getting To The Root Of Cancer

July 27th, 2008 by allsoch

Cancer. Source feinberg.northwestern.eduIn two complementary studies, Weizmann Institute scientists have developed a new method for reconstructing a cell’s ‘family tree,’ and have applied this technique to trace the history of the development of cancer.
The quest to understand a cell’s path of descent, called a cell lineage tree, is shared by many branches of biology and medicine as gleaning such knowledge is key to answering many fundamental questions, such as whether neurons in our brain can regenerate, or whether new eggs are created in adult females.

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First Worldwide Analysis Of Cancer Survival Finds Wide Variation Between Countries

July 27th, 2008 by allsoch

Cancer. Source news.bbc.co.ukBlack men and women have substantially lower survival than white men and women in the United States, but US has the highest survival for prostate cancer of all 31 countries included
Cancer survival varies widely between countries according to a worldwide study published online today in Lancet Oncology.* More than 100 investigators contributed to the study.

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Using Magnetic Nanoparticles To Combat Cancer

July 26th, 2008 by allsoch

Cancer. Source allthingsbeautiful.comScientists at Georgia Tech have developed a potential new treatment against cancer that attaches magnetic nanoparticles to cancer cells, allowing them to be captured and carried out of the body. The treatment, which has been tested in the laboratory and will now be looked at in survival studies, is detailed online in the Journal of the American Chemical Society.
“We’ve been able to use magnetic nanoparticles to capture free-floating cancer cells and then take them out of the body,” said John McDonald, chair of the School of Biology at Georgia Tech and chief research scientist at the Ovarian Cancer Institute.

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Brain Tumors Diagnosed in First Year of Life Linked to Later Complications

July 26th, 2008 by allsoch

Brain Tumors Diagnosed.Source images-cdn01.associatedcontent.comNEW YORK (Reuters Health) Jul 23 - Long-term survivors of brain tumors diagnosed in the first year of life have a substantial risk of neurological and cognitive complications, according to findings published in the July issue of the Archives of Disease in Childhood. These patients are also at risk of social isolation and decreased health-related quality of life.

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HTLV-1 Infection Tied to Reduced Risk of Gastric Cancer

July 26th, 2008 by allsoch

HTLV-1 Infection.Source nature.comNEW YORK (Reuters Health) Jul 23 - The presence of human T lymphotropic virus type 1 (HTLV-1) infection appears to reduce the likelihood of developing gastric cancer, possibly through a modulating effect on Helicobacter pylori activity, Japanese researchers report in the July 1st issue of the Journal of Infectious Diseases.

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High-Dose Immunochemotherapy Safe for HIV-Infected Adults With Burkitt Lymphoma

July 26th, 2008 by allsoch

HIV-Infected.Source inlife.blog.dada.netNEW YORK (Reuters Health) Jul 23 - High-dose immunochemotherapy can safely be administered to HIV-infected patients with adult Burkitt lymphoma, according to a report in the July 1st Cancer.

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